DiscovIR-GC™ with parallel Mass Spectrometry is a uniquely powerful platform for metabolite annotation and unknown/biomarker identification.

By combining chromatographic separation with mass spectrometry and solid-phase FTIR, a structurally informative spectroscopic technique, the DiscovIR-GC™ delivers enhanced Metabolomics Standards Initiative (MSI) Level 2 Annotation, even in complex mixtures/matrices: applications where offline metabolite extraction & purification, or preparative fraction collection for confirmatory NMR analysis, is impractical or impossible.

For true unknowns, MS and IR spectra may be interpreted, to shortlist and rank candidate structures based on molecular formula and functional groups. This approach minimises the number, and cost, of commercially available, or synthesised standards, required to obtain MSI Level 1 identification.
Potential DiscovIR-GC™ applications for metabolomics include the analysis of alkaloids, volatiles/semi-volatiles, terpenoids, FAMEs and simple lipids (sterols, alkanes, alkanols, wax esters, etc).

Spectrometrics are the UK’s leading experts in GC-MS based metabolomics, with over 25-years’ experience running a metabolomics core facility and product managing metabolomics solutions and analysers.

DiscovIR-GC™ for Metabolite ID

email: enquiries@spectrometrics.com